Molecule MO000010: EIN2(A.t.)   General Information Acc No  MO000010 Name  EIN2(A.t.) Full Name  ethylene insensitive2 Class  basic Type  membrane protein Sequence  MEAEIVNVRP QLGFIQRMVP ALLPVLLVSV GYIDPGKWVA NIEGGARFGY   50 DLVAITLLFN FAAILCQYVA ARISVVTGKH LAQICNEEYD KWTCMFLGIQ   100 AEFSAILLDL TMVVGVAHAL NLLFGVELST GVFLAAMDAF LFPVFASFLE   150 NGMANTVSIY SAGLVLLLYV SGVLLSQSEI PLSMNGVLTR LNGESAFALM   200 GLLGASIVPH NFYIHSYFAG ESTSSSDVDK SSLCQDHLFA IFGVFSGLSL   250 VNYVLMNAAA NVFHSTGLVV LTFHDALSLM EQVFMSPLIP VVFLMLLFFS   300 SQITALAWAF GGEVVLHDFL KIEIPAWLHR ATIRILAVAP ALYCVWTSGA   350 DGIYQLLIFT QVLVAMMLPC SVIPLFRIAS SRQIMGVHKI PQVGEFLALT   400 TFLGFLGLNV VFVVEMVFGS SDWAGGLRWN TVMGTSIQYT TLLVSSCASL   450 CLILWLAATP LKSASNRAEA QIWNMDAQNA LSYPSVQEEE IERTETRRNE   500 DESIVRLESR VKDQLDTTSV TSSVYDLPEN ILMTDQEIRS SPPEERELDV   550 KYSTSQVSSL KEDSDVKEQS VLQSTVVNEV SDKDLIVETK MAKIEPMSPV   600 EKIVSMENNS KFIEKDVEGV SWETEEATKA APTSNFTVGS DGPPSFRSLS   650 GEGGSGTGSL SRLQGLGRAA RRHLSAILDE FWGHLYDFHG QLVAEARAKK   700 LDQLFGTDQK SASSMKADSF GKDISSGYCM SPTAKGMDSQ MTSSLYDSLK   750 QQRTPGSIDS LYGLQRGSSP SPLVNRMQML GAYGNTTNNN NAYELSERRY   800 SSLRAPSSSE GWEHQQPATV HGYQMKSYVD NLAKERLEAL QSRGEIPTSR   850 SMALGTLSYT QQLALALKQK SQNGLTPGPA PGFENFAGSR SISRQSERSY   900 YGVPSSGNTD TVGAAVANEK KYSSMPDISG LSMSARNMHL PNNKSGYWDP   950 SSGGGGYGAS YGRLSNESSL YSNLGSRVGV PSTYDDISQS RGGYRDAYSL   1000 PQSATTGTGS LWSRQPFEQF GVAERNGAVG EELRNRSNPI NIDNNASSNV   1050 DAEAKLLQSF RHCILKLIKL EGSEWLFGQS DGVDEELIDR VAAREKFIYE   1100 AEAREINQVG HMGEPLISSV PNCGDGCVWR ADLIVSFGVW CIHRVLDLSL   1150 MESRPELWGK YTYVLNRLQG VIDPAFSKLR TPMTPCFCLQ IPASHQRASP   1200 TSANGMLPPA AKPAKGKCTT AVTLLDLIKD VEMAISCRKG RTGTAAGDVA   1250 FPKGKENLAS VLKRYKRRLS NKPVGMNQDG PGSRKNVTAY GSLG   1294 Sequence Source  translated from cDNA GenBank:AF141203 Sequence Length  1294 Molecular Weight (calc.)  140956.5 IP (calc.)  5.71 Creation  Apr 7 2003 02:17:55:857PM Creator  lb Last Update  Apr 7 2003 03:00:53:000PM Last Updater  lb Reaction Acc No  Name  RE000009  CTR1(A.t.) -/ EIN2(A.t.)  RE000012  EIN2(A.t.) -> EIN3(A.t.)  RE000013  EIN2(A.t.) -> EIL1(A.t.)  RE000014  EIN2(A.t.) -> EIL2(A.t.)  RE000015  EIN2(A.t.) -> EIN3-like(A.t.)  RE000023  MPK6(A.t.) -> EIN2(A.t.)  RE000116  ETR1(A.t.) -- EIN2(A.t.)  RE000122  ETP1(A.t.) -/ EIN2(A.t.)  RE000123  ETP2(A.t.) -/ EIN2(A.t.)  RE000356  ECIP1(A.t.)--EIN2(A.t.)  Plant Acc No  PL000002 Name  Arabidopsis thaliana Hyperlinks Database  Link  UniProt  Q9S814 PIR-NREF  NF00651083 GenPept  AAD41076.1 GenBank  AF141203 Comments pathway  Map of the Arabidopsis thaliana ethylene pathway pathway  Computer-generated pathway map Location Located in  Score  Reference  ER membrane, N.b.  2, QU000195  Ref. 1 References Ref. 1   Acc No  RF000453   Authors  Bisson MM, Bleckmann A, Allekotte S, Groth G.   Title  EIN2, the central regulator of ethylene signalling, is localized at the ER membrane where it interacts with the ethylene receptor ETR1.   Source  Biochem J 424: 1-6. (2009) Ref. 2   Acc No  RF000130   Authors  Alonso JM, Hirayama T, Roman G, Nourizadeh S, Ecker JR.   Title  EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis.   Source  Science 284: 2148-52 (1999)