Reference RF000119
General Information
Acc No RF000119
Journal Cell
Authors Hua J, Meyerowitz EM.
Title Ethylene responses are negatively regulated by a receptor gene family in Arabidopsis thaliana.
Volume 94
Issue 2
Page 261-71
Year 1998
Abstract A family of genes including ETR1, ETR2, EIN4, ERS1, and ERS2 is implicated in ethylene perception in Arabidopsis thaliana. As only dominant mutations were previously available for these genes, it was unclear whether all of them are components in the ethylene signaling pathway and whether they code for positive or negative regulators of ethylene responses. In this study, we have isolated loss-of-function mutations of four of these genes (ETR1, ETR2, EIN4, and ERS2) and identified an ethylene-independent role of ETR1 in promoting cell elongation. Quadruple mutants had constitutive ethylene responses, revealing that these proteins negatively regulate ethylene responses and that the induction of ethylene response in Arabidopsis is through inactivation rather than activation of these proteins.
PMID 9695954
Corresp Author Meyerowitz EM
Corresp Email
Creation Jan 13 2003 07:00:30:153PM
Creator lb
Last Update Jan 27 2003 04:21:15:000PM
Last Updater lb
Database  Link 
PubMed  9695954